(NOTE: because of the overly-excessive promotion and hype by those affiliated with the company that make anatabine, I am not allowing any more posts and have removed others. There are many other successful ways to lower inflammation other than just this product.)
What if there was a dietary supplement that was proven to greatly slow your immune system from attacking your thyroid, and which greatly reduces inflammation?
On January 7th, the results of a Human Thyroid Study by Star Scientific, Inc/Rock Creek Pharmaceuticals was announced about the successful use of the supplement anatabine in doing just that.
What is anatabine? It’s a chemical compound called an alkaloid, of which anatabine is a minor plant alkaloid. Alkaloids are also found in certain plants like poppies, besides found in fungus, bacteria and animals. Caffeine and Nicotine are even examples of major alkaloids, as are cocaine, quinine and strychnine (so you can see that for all the positive qualities of aldaloids also come negative ones if used carelessly). Anatabine, believe it or not, can be found in tobacco and tobacco smoke.
The study occurred in a “three-month, five-visit, double-blind, placebo controlled” environment of nine sites. Subjects in this study, which included 148 individuals with proven Hashimotos inflammation, were given 9 – 24 mg of anatabine based on their weight.
The results?
Supposedly, anti-thyroglobulin antibodies went down as did thyroid nodules. The results were very promising after only three months, giving pause of what the supplement could do if taken longer. We are waiting on the full study to come out, so you might not want to jump the gun. Hype doesn’t also equal reality.
P.S. The European Journal of Pharmacology also reported last November that anatabine suppressed the brain inflammation common with Alzheimers.
WHERE TO FIND INFLAMMATION LAB WORK
Whether you have Hashimotos or not, it’s all-too-common for thyroid patients to find themselves with high levels of inflammation as discovered by certain lab work, such as a high ferritin result or a positively high C-Reactive Protein (CRP).
And why is chronic inflammation a concern? Inflammation can spread and affect far more than a localized area. It can result in dampening of your HPA axis (meaning you won’t signal your adrenals well to produce cortisol), higher blood pressure, allergies, autoimmune issues, joint pain, heart problems, harmful swelling, bone loss and so much more that is negative to your health and well-being.
Where to order your own inflammation labwork: Inflammation Numbers (CRP, ESR, Ferritin) $99 https://sttm.mymedlab.com/
How to treat inflammation? A common reason for many Hashimotos patients is the continued consumption of gluten-containing foods. The majority of Hashi’s patients have to get completely off gluten to control their inflammation. Some patients avoid milk products to reduce inflammation.
Having candida is a common inflammation problem brought about my continued hypothyroidism (especially for those on T4-only meds, or underdosed even on NDT), so aggressively treating with anti-fungus meds or anti-inflammatory supplements is important. Your doctor can help you with that.
High dose Omega 3 has had good results, report patients, in lowering inflammation, as has combined herbs such as turmeric and ginger. Krill Oil, such as 3000 mgs, in combination with any of the above, has been reported as successful by some patients.
Astaxanthin, an antioxidant supplement growing in popularity in reducing inflammation, is growing in popularity by patients. It occurs naturally in some algae and is the reason you see the red or pink in shrimp, salmon or other seafoods.
For more difficult cases, some patients have turned to prescription meds like Amantadine. Talk to your doctor about any of the above anti-inflammatories.
30 Responses to “A supplement that reduces autoimmune Hashimotos? And here are inflammation labs you should consider!”
Jennifer Carroll
Where would I find this supplement? If I have already been diagnosed with hypothyroid, would it still help?
(From Janie: I would use your favorite search engine and see what you find.
)
Mathew
Amazon or GNC has it as Anatabloc. I wonder why more folks aren’t talking about this study?! Seems very exciting!
“Data from this rigorously conducted, placebo-controlled, double blind trial show that anatabine-treated subjects had progressive decreases in circulating thyroglobulin antibody levels, which became significant by the end of the trial. Current treatment for autoimmune thyroiditis is limited to end-stage disease when irreversible gland damage necessitates lifelong thyroid hormone replacement. The prospect of a novel nutritional or pharmaceutical intervention that could preserve thyroid health represents an encouraging advance. Further clinical studies are now warranted.”
Lori
very expensive supplement $99.00 a bottle!!
Amy
But have you seen what other ingredients are in Anatabloc?
From GNC webpage:
Mannitol, Natural and Artificial Mint Flavors, Sucralose, Silicon Dioxide, Stearic Acid, Hydroxypropyl Methylcellulose, Magnesium Stearate, Titanium Dioxide (color), Natural Glaze, METHYLPARABEN, PROPYLPARABEN, Triethyl Citrate, Citric Acid, BHT, Mono and Diglycerides, Polysorbate 80
Should it really contain parabens?
(From Janie: keep in mind that what they used in the study may not be the same mixture as what GNC is making or what you are currently finding on the internet)
Carrie
Amazing that this supplement lowers thyroglobulin antibodies. Does anybody know if the study proved that it also lower TPO antibodies?
(From Janie: You’d think so. Remember that we are dealing with a medical community which has repeatedly thought that testing ONE of the two thyroid antibodies was enough to diagnose Hashi’s…as many thyroid patients have reported was sadly done to them, only to later find out that the one NOT tested was high even though the one tested was not. So perhaps this is just one more example of what they do—testing one, sadly. But the implication from that one is still good.)
Bob Clarke
I have hypothyroidism, and have been taking Anatabloc for about 7 months. I am not totally off Armour, but the dosage has been cut in half, and general CRP and cardiac CRP levels are at the bottom of the range (that’s a good thing). More tests will be done in April for follow-up.
Since Anatabloc works on general inflammation processes, I have noticed that muscle soreness from working out no longer occurs, and minor nagging pain from jogging no longer occurs, either. So, yes, it is not cheap, but it works on more than just thyroid problems.
Me
The ingredients of the current GNC product are problematic. Without even considering any of the other ingredients, the fact that it has Sucralose (Splenda) is so disappointing. The are marketing to folks that can think out of the box but are adding in ingredients We wouldn’t touch with a ten foot pole.
Adam, can you tell us where you see the info about reformatting the product? I would love to read more about that.
Janie
http://seekingalpha.com/instablog/576542-dr-john-faessel/1026321-star-scientific-stsi-anatabine-101-the-trend-is-your-friend
JD
Janie, do you have an additional info on Amantidine? Studies ect? My doctor has me on 100mg bid. It has helped me tremendously for my hashis. My TPO is down to 60 and has helped many of my symptoms.
(From Janie: JD, we’re all learning together. So if you find anything, post it here.)
Paul Edman
Star Scientific Thyroiditis Data Published
First, preliminary results of the study, yet to be peer-reviewed and published, provide the most compelling evidence yet that Anatabloc is what I’ve said it is — the first effective therapy for endemic autoimmune disorders. While this study demonstrated the first-ever ability to reverse the course of thyroiditis, its importance is in its ability to treat or prevent autoimmune disorder, which plays a role in virtually all age-related diseases, including thyroiditis.
Second, the famously cautious Dr. Paul Ladenson, one of the top endocrinologists in the world, has gone on record saying, “Data from this rigorously conducted, placebo-controlled, double-blind trial show that anatabine-treated subjects had progressive decreases in circulating thyroglobulin antibody levels, which became significant by the end of the trial.”
Dr. Curtis Wright, Medical Director for Ross Creek Pharmaceuticals, said:
“It is remarkable that dietary supplementation is able to help lower the thyroid antibody activity. To see antibodies that may have been elevated for years beginning to come down in a significant way after three months of supplementation is exciting. Given the rate of decline over three months, it is quite reasonable to expect that the effect may continue with longer use, which has already been observed in individual cases. I look forward to following subjects over a longer period in order to establish how profound and clinically meaningful the effect is going to be. The thyroglobulin levels in some patients returned entirely to normal in this three-month study.”
Mike L
Blood Lab results 12/20/2012
63yrs next month. These results are a miracle for me compared to before anatabine. Started with CiGRX in March of 2011 then Anatabloc when it became available. I’m jazzed to see that I can get 300 count now at GNC for the old price of 200.
GLYCOHEMOGLOBIN GLYCO 5.3 %T.Hgb
CHOLESTEROL CHOL 142 mg/dl
TRIGLYCERIDES TRIG 124 mg/dl
CHOLEST/HDL RATIO.. CHO/H 3.64
HDL* HDL 39 mg/dl
LDL NLDL 78 mg/dl
NON-HDL CHOLESTEROL 103 mg/dl
FREE T4 FREET4 1.3 ng/dl
TSH. 7580 2.00 mIU/
joyce m
I’m on Anatabloc 7 days now and will continue with it…have felt some Relief in 5 days…
I deal with FM, OA and hip surgery complications…lots of chronic inflammation.
Am on Armour since 2002 and deal with Hashi.
I can only get 200 ct from the company….is the 300 ct still being sold…..
Alice
Anti inflammatories are great but they don’t reduce hashimoto’s. It still very important to determine what’s CAUSING the inflammation. Food sensitivities are a major culprit. Don’t stress about getting the antibodies down….that isn’t an indication of successful treatment. As a TH2 dominant hashi, I’ve felt absolutely wonderful with antibodies over 14,000 and horrible when they were half that.
(From Janie: your experience isn’t going to be true for everyone, since antibodies can spread elsewhere, and since folks have reported that lowering their inflammation did lower their antibodies).
Razzle
Essential oils can also lower inflammation quite effectively.
I’ve been having arthritic swelling and pain in my hip, but when I apply essential oil of Copaiba topically on the area of my hip that hurts, the pain is completely gone within seconds.
According to a presentation I went to about essential oils, medical grade Copaiba essential oil is a more powerful anti-inflammatory than Prednisone.
And my experience seems to back this up, as I have been on Prednisone before and not had such excellent relief from inflammation in my joints.
Amy
Greetings, I too called the makers of Anatabloc and was told that they are indeed reformatting their formula to eliminate some of the ingredients (such as parabans). They do not have a date for this, but said it will be 2013.
I started the supplement and was on it for 5 days when I stopped for a cleanse recommended by my health coach – but am back on it because my hash’s symptoms are off the chain (especially the mood swings, irritability, fight or flight type overreaction). Will check back in and let everybody know….
Adam Reynard
Most people are not taking proper dosage. Extremely important to be on correct dosage. The company has learned a lot through their clinical studies.
Label Facts—The new 300 lozenges bottle available from GNC has the following label information:
RECOMMENDED DOSAGE: 100-120 LBS=2 lozenges 3 times daily (6); 121-170LBS=2 lozenges 4 times daily (8); 171-220LBS=2 lozenges 5 times daily (10), and 221LBS+=2 lozenges 6 times daily (12).
joy martino
I’m getting Positive results on Anatabloc after 2.5 weeks….I posted on Janie’s Health Boards and they
knocked me off for advertising…
I don’t get it…
joy martino
To add to my 2/1 post, and I didn’t realize I was on here before…these blogs get confusing, blogs, discussion groups, so much for an old gal to absorb.
Anyway, last night I took 3 loz under my tongue and woke up 9:30AM feeling NO PAIN and I deal with OA, FM and surgery complications = inflammation. My pain was waking me at 4-5-6AM and sometimes 3AM prior to Anatabloc. Somethings working…take less advil and that is good.
I will be taking 7 daily now and see how that goes….glad to see the company is giving us 300 for the same price and I get the unflavored….
Theresa
Maybe this is why smokers promptly gain weight after quitting? Coincidence?
Georgie
I was sick as hell after quitting smoking. Developed hypothyroidism, very severe symptoms. Have been dealing with it ever since. I always said that quitting smoking made me ill (although of course there were a lot of benefits, too) and I wondered if there was something about tobacco that had been keeping my body in balance. So I read this article and thought ‘bingo!’ That explains it!
Skeptic
Folks, I’m a big fan of diet and supplements for addressing autoimmune inflammation, but this Anatabloc supplement sounds like a bunch of BS. They clearly are paying people to troll all the autoimmune forums and sell people on false claims and false hope. I have seen this fake advertising, full of personal accounts of miraculous healing, then links to bogus-looking websites about Anatabloc (although they finally have a shnazzy new website). This supplement is being studied and marketed by one shady supplement company, and they need sales at GNC and investors to make their product and company a success. At this point, it’s one massive human experiment (those people buying it at GNC), because the real studies by reputable researchers are still in the works. Proceed with great caution!
Mathew
I’m planning on doing my own study on anatabine’s effects on me. Keeping as much the same in routine and diet as possible, only adding the recommended dose of anatabine to see what happens to blood levels and energy. Anyone else going to do the same and want to compare before/after results?
Angela Galbreath
I am also concerned about the inclusion of sucralose and the parabens. I certainly hope they change that formulation. Does anyone know of another source of anatabine besides through use of Aanatabloc?
Jill
I got a sample 2 weeks ago. So far the only thing I have noticed is that my monthly fibroid flare up during PMS has stopped. First month in 9 since it started they have swelled up like ballons. I didn’t even realize it was that time again. No change in my hashimotos symptoms yet and I haven’t been stable since September, my meds keep getting increased.
skeptic
Oh, my, all the same people trolling and spamming about this product. They must all be investors…
me
Anyone have any new results to report while using Anatabloc?
boehml
If anatabloc is anatabine, why not use natural anatabine like belladonna?
Not rudely asking just wondering the difference besides about 90.00 dollars.
tamara
I didn’t see any mention of Kombucha to decrease Hashimotos antibodies? Any reactions?
Anne Stewart
Kombucha tea is not shown to effect the thyroid or alleviate hypothyroid symptoms. Google. This is human clinical study for Anatabloc. Amazing results.
Beth
I tried this product for 2 weeks and the only thing I noticed was awful gastro issues. I am sure it was the splenda in the product. I agree with other posters, I think that they are getting their own people to post bogus claims. The mere fact is this product has splenda in it, which is loaded with GMO’s and other chemicals.