Did you know that there were deca­des of suc­cess­ful treat­ment for hypothy­roid that invol­ved nothing more than dosing you by symp­toms?  The TSH lab didn’t even come into exis­tence until the mid-1970’s.

Today, the tables have com­ple­tely tur­ned. We now live in a lab-obsessed society, where most doc­tors com­ple­tely ignore your thy­roid symp­toms and make your man-made lab results the holy grail of diag­no­sis. And diag­no­sis and treat­ment based solely on lab­work for thy­roid is a con­sis­tent fai­lure, lea­ving millions of patient either undiag­no­sed, or under­trea­ted.

Even worse, when labs are used, the majo­rity of doc­tors are only doing the TSH (thy­roid sti­mu­la­ting hor­mone) and total T4 to diag­nose or treat you, neither which give an accu­rate clue to your hypothy­roid con­di­tion. Addi­tio­nally, ran­ges are made the “end-all” of nor­malcy. Who rea­ding this hasn’t been told they are “nor­mal” because an ink spot on a piece of paper falls within a dubious range, yet your body screams with NON-normal symptoms?

So…when you visit your doc­tor, you have to be outs­po­ken about your symp­toms. Symp­toms should be the con­duc­tor of the orches­tra, and labs are simply adjuncts for more know­ledge. Then, when labs are men­tio­ned, below are those we recom­mend you insist to your doc­tor that you want. Farther down, you can see expla­na­tions of all labs.

* TSH But this lab is only for diag­no­sis of hypo­pi­tui­tary, NOT to diag­nose or dose your hypo by.
* Free T4 and Free T3 (note the word “free” – important.)
* Thy­roid Anti­bo­dies (anti-TPO and TgAb. YOU NEED BOTH.)

And add these in, since they can be low in thy­roid patients:

* Ferri­tin (and do stress FERRITIN, not just RBC)
* Adre­nal Cor­ti­sol levels (but we strongly recom­mend saliva tests, not the one time blood test your doc­tor will do. See below, because you don’t need a presc­rip­tion)
* B-12 and Folate
*RBC Mag­ne­sium and Potas­sium
* Vita­min D (25-hydroxyvitamin D lab test…plus others your doc­tor may recommend.

* Reverse T3 (to be tes­ted when your Free T4 is in the upper part of the range with con­ti­nuing symp­toms. You need to do it at the same time you do free T3 to mea­sure the ratio)

Below are lab faci­li­ties you can use without a presc­rip­tion. Most are saliva tes­ting, some are blood tes­ting, and another is both saliva and blood – the STTM lab pac­ka­ges!  (Saliva is highly recom­men­ded to test cor­ti­sol. Sali­vary glands have a high blood flow, and the “free” hor­mo­nes from your blood (red blood cells and plasma) easily fil­ter through your saliva glands into saliva where they can be mea­su­red accu­ra­tely. So saliva tests bet­ter reflect your free and usea­ble “bioa­vai­la­ble” hor­mo­nes in your blood, thus making them more rele­vant.)  We do not recom­mend saliva for sex hormones.

NOTE: some of these faci­li­ties are requi­ring a presc­rip­tion for a Reverse T3 test. Sad.

  1. Healthchecklogo LAB WORK pac­ka­ges desig­ned spe­ci­fi­cally for rea­ders of Stop the Thy­roid Mad­ness. Use the dis­count code STTM10 which will give you 10% off the already low pri­ces! STTM Thy­roid and Adre­nal Lab Pac­ka­ges You can choose just saliva for cor­ti­sol, or use Lab­Corp faci­li­ties around the US for blood draws.
  2. LAB WORK pac­ka­ges desig­ned spe­ci­fi­cally for rea­ders of Stop the Thy­roid Mad­ness -STTM Thy­roid and Adre­nal Lab Pac­ka­ges You can choose just saliva for cor­ti­sol (which is six times in a 24 hour period), or use Lab­Corp faci­li­ties around the US for blood draws.
  3. LAB WORK from ZRT LABORATORIES Saliva and a blood prick test…or one or the other. Adre­nal Func­tion Test for cor­ti­sol.  The blood spot test kit uses a fin­ger prick and seve­ral tests can be done from a sin­gle sam­ple. They state it’s on par with serum needle blood draw tests, though you can do this right in your own home. THIS IS ALSO A PLUS SINCE SALIVA CAN FAIL TO DETECT THYROID ANTIBODIES. One down­fall: it’s at least $100 more expen­sive than saliva. http://www.salivatest.com/
  4. LAB WORK from Direct Labs/Sabre Scien­ces. Use the Hor­mone Panel-Female, which will do 7 sam­ples for estra­diol and pro­ges­te­rone, 1 sam­ple for tes­tos­te­rone, 6 sam­ples for cor­ti­sol, and 3 sam­ples for DHEA, collec­ted at desig­na­ted days and times. Also inc­lu­ded is the Elec­trolyte panel of sodium, potas­sium and chlo­ride. $307 www.directlabs.com/ Or you can just do the Spe­cial Thy­roid Panel (for­get their Com­plete Thy­roid Panel – it also adds the use­less T3 uptake, T7 and total T4).
  5. LAB WORK from Vita­min Research Pro­ducts Saliva Test kits inc­lu­ding iodine, adre­nals. They can do New York residents.
  6. LAB WORK from Canary Club.  This web­site is not a lab, but offers saliva for cor­ti­sol, plus more. Saliva for anti­bo­dies or female hor­mo­nes not recom­men­ded by many patients. Shows screwy results. (Canary Club used to offer Diag­nos, Tech, but as of late March 2009, they are remo­ved.  Pro­bably a good thing, since some patients were fin­ding results through Diag­nos Tech which did NOT match their symp­toms or other saliva results.)
  7. Fin­land: Test kits from Genova diag­nos­tics via MDD Ter­veys­pal­ve­lut: http://www.mdd.fi/
  8. Ger­many: Saliva tes­ting and help­ful faci­lity http://www.hormonselbsthilfe.de/
  9. Uni­ted King­dom Lab­work from Lab21: Click on Che­mi­cal Bioche­mistry to find Saliva:   http://www.lab21.com/healthcare/index.php#
  10. Uni­ted King­dom Lab­work from Red Apple Cli­nic. Thy­roid, Adre­nals, and others. (thanks to Crunchie for this info). www.redappleclinic.co.uk
  11. Aus­tra­lian Lab­work from Analy­ti­cal Refe­rence Labo­ra­to­ries (ARL) or Path­Lab You can order the kits your­self, but you won’t be cove­red by Medi­care (natio­nal public health insu­rance) so you have to pay in full. Or you can con­vince your doc­tor. Just ring either of these labs and ask what doc­tor in your area uses their kits. ARL: 568 St Kilda Road Melbourne,Victoria, Aus­tra­lia, 3004; (61 – 3) 9529 – 2922; fax (61 – 3) 9529 – 7277 info@arlaus.com.au. or Path­Lab: 68 Bur­wood High­way, Bur­wood, Vic­to­ria 3125, (61 – 3) 8831 – 3000; Fax (61 – 3) 9808 2247; (Nutri­tio­nal Labo­ra­tory Ser­vi­ces), Ed Sorich Inte­gra­tive Medi­cine Dept; www.pathlab.com.au
  12. Curious about your D levels? Go here: www.virginiahopkinstestkits.com/vitamindtest.html or you can use the STTM labs in #1 and #2 above for Vit. D and B-12 with a dis­count through Healthcheck.

NOTE: seve­ral labs above pro­vide you with the term “Cor­ti­sol Bur­den” and a num­ber. Cor­ti­sol Bur­den is the com­bi­ned value of all 4 saliva cor­ti­sol rea­dings for the awake period of that par­ti­cu­lar day. It can tell you if you are making more or less than the ave­rage.

ABOUT RANGES: Each lab faci­lity can have dif­fe­rent ran­ges, so it’s impor­tant to eva­luate YOUR results by the ran­ges pro­vi­ded by the lab faci­lity you used. But, we espe­cially like the free T3 repre­sen­ted on this page, since the free T3 range is espe­cially wide!! Dr. Domis­see of Ari­zona remem­bers using a lab that also had a range more like this one, and we hope to see a return of this. The current free T3 ran­ges are often far too narrow!

***CLICK HERE TO READ HOW TO INTERPRET YOUR LAB RESULTS.

TSH: This is the abbre­via­tion for Thy­roid Sti­mu­la­ting Hor­mone, and is also known as thy­ro­tro­pin. It’s pro­du­ced and sto­red in the Pitui­tary gland, and is relea­sed to sti­mu­late your thy­roid to release more hor­mo­nes. When your TSH rises high, it means your thy­roid isn’t doing it’s job, and the TSH is saying “Pro­duce! Pro­duce!” On the other side of the coin, when the TSH goes low, it can mean your thy­roid is over­pro­du­cing, called hyperthy­roid. But remem­ber: there’s a huge dif­fe­rent bet­ween the REAL TSH in your body, and the TSH lab test. Patients have con­sis­tently found the TSH lab to be a lousy mea­sure, and more spe­ci­fi­cally because of a ques­tio­na­ble “nor­mal” range, cau­sing a patient to go for years without diag­no­sis. Addi­tio­nally, the TSH often lags behind what is really going on, or it can be affec­ted by fac­tors inc­lu­ding hypo­pi­tui­tary, acute stress, extreme ill­ness, or the first tri­mes­ter of preg­nancy, etc. Addi­tio­nally, you can have a very low TSH during a one time lab test, yet have an untes­ted high TSH a few days later. That fluc­tua­tion is indi­ca­tive of Hashimoto’s or an attack of the thy­roid, cau­sing swings bet­ween hypo and hyper. And once you start on treat­ment, patients have noted that when they are kept within the range – even at the lower end – they con­ti­nue to have symp­toms! It is totally use­less? No. A low TSH lab test in the pre­sence of a low free T3 and symp­toms to match hypothy­roid can point to hypo­pi­tui­tary. This con­di­tion means your pitui­tary fails to send a mes­sage via the TSH to your thy­roid to pro­duce. Cau­ses can range from a tumor on the pitui­tary gland, to severe head trauma, to radia­tion, sur­gery or infec­tion. Go here to read more.

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ARE YOU A SMOKER??? There is evi­dence that those who smoke have a lower TSH than those who don’t. That can be a disas­ter in our TSH-obsessed society, and your diag­no­sis of hypothy­roid can wane. So there is wis­dom in refrai­ning from smo­king the day of your lab blood draw. To see a research study on smo­king and your TSH, go here.

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Free T4: T4 is the sto­rage form of thy­roid hor­mone, called levothy­ro­xine or l-thyroxine, and it’s “main” pur­pose is to con­vert to the active hor­mone T3. There are two llabs: one will simply say T4, and the other will say free T4. If you only have the T4, aka the total T4, you are mea­su­ring both bound and unbound T4, and it fails to tell you what is free and usea­ble. The free T4, on the other hand, shows the lat­ter. Make it clear to your doc­tor that you want the FREE.

Free T3: T3 is the active thy­roid hor­mone, also called triio­dothy­ro­nine, and can be the most impor­tant lab you will do. Same as above, you need to spe­ci­fi­cally request the free T3 to reveal what is unbound and avai­la­ble. You can have a so-called nor­mal TSH, but if your free T3 is low in the range, that is a strong sign of your hypothy­roid sta­tus. Though most of the T3 in your body is pro­du­ced by the con­ver­sion of T4 to T3, there is also a direct release of T3 from the thy­roid. T3 is the active hor­mone which is res­pon­si­ble for your ove­rall good health, meta­bo­lism, immune strength, etc. A good level of T3 is what pre­vents chro­nic low grade depres­sion, high cho­les­te­rol, dry skin and hair.…the list is end­less. When patients are rai­sing their Armour, their opti­mal dose is most often the amount that gets their free T3 at the top of the range, if not slightly over in some patients, with no hyper. The free T4 is often mid-range, and the TSH is most often sup­pres­sed. The lat­ter does NOT equate to having osteo­po­ro­sis or heart pro­blems, as many unin­for­med doc­tors will rotely state. Ins­tead, patients have repor­ted their bone den­sity IMPROVED, as did some heart issues.

ANTIBODIES: Anti­bo­dies are pro­teins pro­du­ced by your immune sys­tem in res­ponse to a pro­blem. If your labs come back above-range for thy­roid anti­bo­dies, you can have an autoim­mune thy­roid disease, also called thy­roi­di­tis or Hashimoto’s, which means your thy­roid is being attac­ked. There are two forms – one set tar­ge­ting your thy­roid pero­xi­dase (an enzyme that is impor­tant in the pro­duc­tion of your thy­roid hor­mo­nes) and the other tar­ge­ting your thy­ro­glo­bu­lin (a pro­tein carrier for your thy­roid hor­mo­nes). It is not uncom­mon for one to be in range, and the other to far out of range. The lat­ter fact is why you need BOTH tes­ted. Make sure you are taking Sele­nium, since stu­dies show it can help reduce the TPO anti­bo­dies. I have not yet found research as to if it can lower the thy­ro­glo­bin anti­bo­dies. Even with the pre­sence of anti­bo­dies, you can ini­tially have a so-called “nor­mal” TSH and the lack of symp­toms. But down the line, you WILL get symp­toms of the attack, which can inc­lude vaci­lla­ting bet­ween hypo and hyper, and even­tually beco­ming a raging hypo. So, it’s impor­tant to “tac­kle the attack”, and patients have found great suc­cess when they are willing to dose high enough with Armour. Armour, when rai­sed high enough, appears to remove the sig­nal that crea­tes the attack.

IMPORTANT: if your labs show that you have anti­bo­dies, all lab­work has to be thrown out the win­dow when it comes to using them for diag­no­sis. Why? Because anti­bo­dies mean an attack is going on, and an attack means you will swing bet­ween hypo and hyper. One lab will look hyper, and the unk­no­wing doc will tell you to dec­rease your Armour…when in rea­lity, you need to INCREASE your Armour to even­tually STOP the attack. With anti­bo­dies pre­sent, you have to dose by the eli­mi­na­tion of symp­toms, NOT labs. A large goi­ter or thy­roid gland can accom­pany some cases of Hashi­mo­tos. Or, you can feel a dis­com­fort when you swa­llow, and a tight­ness around the neck area. Ele­va­ted thy­roid anti­bo­dies have been lin­ked to a wide array of non-thyroid disea­ses inc­lu­ding chro­nic inflam­ma­tory bowel disease and diabetes.

CORTISOL and FERRITIN

ADDITIONAL LABS TO CONSIDER: Many thy­roid patients have bene­fi­ted from get­ting other lab­work, inc­lu­ding DHEA, tes­tos­te­rone, pro­ges­te­rone, estro­gen. The crea­tor of this site found her tes­tos­te­rone to be quite low, even though she had no symp­toms of it. Her doc­tor hel­ped her start sup­ple­men­ta­tion and she found the sur­prise result of the com­plete remo­val of low back pain upon waking. Other female patients with low sex dri­ves found that the tes­tos­te­rone sup­ple­men­ta­tion rene­wed their dri­ves. We are seeing more labs being done for Vit. D, as well as other mine­rals. Highly recom­men­ded. *To read a good article on Saliva vs. Blood tests, go here.

*Click HERE to see OPTIMAL LAB VALUES…i.e. what your lab results mean and where you want to be.

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