As the one grain tabs of Naturethroid desiccated thyroid by RLC Labs are hitting pharmacy shelves again all across the nation here and there after the recent shortages and the sad reformulation of Armour, and patients are starting to use the new Naturethroid, we are gathering some good information, both anecdotal and factual:
- The typical smell of desiccated porcine is less intense with the new tablets. We have no idea why.
- The tablets are now stamped with RLC on one side, and N over 1 on the other, whereas before you’d see just NT1 or a reference to the fact that Time Caps Labs (TCL) used to make Naturethroid for RLC Labs
- The package insert is no longer inside the bottle but stuck on top of the cap
- Lot number info used to be on the edge of the label running vertically, whereas now, it runs along the bottom of the label under the ingredients.
One grain is still 65 mg, with the T3 content being at 9 mcg and the T4 content being at 38 mcg. The T2, T1 and calcitonin still unmeasured.
There are filler/inactive ingredients which have changed:
- Calcium filler has moved up from 16 mg to 17 mg (calcium binds thyroid, but you just take more. Don’t swallow it with milk, please.)
- The old contained Magnesium, Potassium, and Sodium (each at less than 1 mg), whereas in the new, potassium is now removed
- And here’s the best part: the old NT had Hydropropyl Methylcellulose – that’s the larger size cellulose structure which we know binds some of the thyroid hormones. Now, the new NT has Microcrystaline Cellulose, the smaller size. (Too bad we can’t see all cellulose removed!)
Below are the new NT fillers, which are identical to the old except for the cellulose change:
Carnaba Wax, Colloidal Silicon Dioxide, Dicalcium Phosphate, Hypromellose, Lactose Monohydrate, Magnesium Stearate, Microcrystaline Cellulose, Polyethylene Glycol (PEG)-400, Sodium Starch Glycolate, Stearic Acid.
Most all the above comes courtesy of Stephanie Buist, owner of the Iodine group on Yahoo and thyroid and adrenal patient and advocate. Thank you, Steph! You can read about the fillers here by scrolling down.
Oh and by the way, the new tablets are now scored. A helpful addition!
In patient groups, we are seeing a variety of experiences with the new Naturethroid. Most folks seem happy with it so far, and even some report it seems a tad stronger than the old (the cellulose change may have caused that). Occasionally, someone will report problems, but they appear to be from underdosing or a potential RT3 problem which has arisen and needs treatment with T3-only. Changing brands can also bring different reactions, so you have to wiggle the dosage around sometimes to find your sweet spot once again.
All in all, it looks good.
P.S. If you are reading this via the Newsletter Notification, just click on the above link to put yourself right on the actual blog post if you want to comment. Let’s gather all our experiences with the new Naturethroid.
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If you missed the last internet radio Thyroid Patient Community Call with Dr. Kent Holtorf, you missed a VERY good one. Thank you Dr. Holtorf for excellent information. But good news! All the shows are recorded. Just go to the following link, scroll down, and you can click on any past interviews, including two with Dr. John C. Lowe and a great one with Endocrinologist Dr Pepper – one of a rare breed of open-minded Endos. (I’ve also stopped doing my long intro’s about me in the last two, figuring if someone wants to know, they can go to the About Me page, or read the Introduction in the book which has even more detail. lol.)
http://www.talkshoe.com/talkshoe/web/talkCast.jsp?masterId=62603&cmd=tc
Jan said:
Feb 20, 10 at 3:49 pmSo basicly what you are sying is that Nature-Throid has also been reformulated?
(From Janie: perhaps, but not with the negative connotation that we got with Armour)
Michele said:
Feb 20, 10 at 5:09 pmAfter finding Armore was changed (and due to shortages) I had a month or two on Naturethroid which was great…had to go to new Armore for a month…and felt myself go slowly down hill…and just got Naturethroid again. I have to say I’ve been surprised at it not working as well as before…thought… something is different I think…I seem to need more…will see how that goes…pleeeeassse!
Carol G. said:
Feb 20, 10 at 6:30 pmI see in the ingredients that there is lactose monohydrate in Naturethroid. From what I could find it appears that is a milk derivative. Being allergic to milk products I always have to wonder why they would put milk derivative in medicine?? I did better on Naturethroid than the new Armour but still not near as good as I did on the old Armour. Now I’m on compounded and aching all over…after reading this I’m thinking I need to find out what they are putting as filler in my compounded. Thanks for the information it’s been very helpful.
annie phenix said:
Feb 20, 10 at 8:27 pmI haven’t done well on Naturethroid since I switched from the new Armour last summer. I had several hypo symptoms come back
I am now trying compounded Armour and so far so good. The only filler the pharmacy put in was acidopholis. I am sick to read that the makers of Naturetroid put a milk derivative in it as I can’t have milk/caseins either. Maybe that is why I haven’t done well on Naturethroid? I very much appreciate your pointing that out, Carol G.
Lethal Lee said:
Feb 21, 10 at 5:40 am(From Janie: Hi Lethal. I think you misread the information. They state they only switched from methyl to micro, not increased it. But it’s too bad that any has to be in there at all. Agreed.)
Microcrystaline Cellulose is also the SAME type of cellulose that is in in Armour.
The recent Armour reformulation reduced Dextrose & INCREASED the Microcrystaline Cellulose content and THAT caused all the problems we are all well aware of.
Why then is the Microcrystaline Cellulose in the NT any different? Why would they increase Cellulose at all when they are aware of the Armour fiasco?
http://www.stopthethyroidmadness.com/2009/11/11/is-cellulose-the-real-problem/
See blog
One person has commented that new NT is chalkier & you say it smells less piggy too. Doesnt this sound just like the comments made for new Armour?
Avicel is a brand of Microcrystaline Cellulose & is often used in the compounded NTH (certainly the case in Australia). That is certainly problematic.
In fact on RTH we are advising folks to avoid cellulose of any kind. Much better to have Acidophilus for example.
As far as Lactose goes ALL NTH meds including compounded, contain trace amounts of it. It is in the Thyroid USP powder itself.
See..
■Lactose Monohydrate — traceable amount as part of desiccated thyroid powder USP
http://www.stopthethyroidmadness.com/armour-vs-other-brands/
Sally said:
Feb 21, 10 at 11:42 amAm just starting on compounded and they switched filler for me to bioflavinoid. Hoping it works well and i will feel well.
Did not know about the trace Lactose in Thyroid USP powder.
All very interesting. THank you!
Jenny said:
Feb 21, 10 at 7:02 pmSo is lactose added as a filler a problem or not? I just called my compounding pharmacy, and they said they don’t add cellulose but use lactose as the filler. They argued that there was absolutely no problem with lactose as a filler. Does it bind with the thyroid?
Meg said:
Feb 22, 10 at 4:30 am@Sally
meg
As compounded has recently become an option in Norway (alliance apotek), I’m interested in fillers.
Do you know what it is, the bioflavinoid your farmacy is using?
Thanks!
Nickie said:
Feb 22, 10 at 9:09 amI was only on Nature-throid for a short time but I didn’t see too much of a difference but have talked to someone who had really bad side effects and actually felt worse than she did before she started on Armour — said all her symptoms came back. She is now on the compounded dessicated thyroid and had a problem adjusting to that for the first week and now doing great. Maybe it’s just that the body has to get adjusted to the new thyroid supplement. I am doing much better on the natural dessicated thyroid from the compounding pharmacy than I did on the Nature-throid and I’m also allergic to cow milk so I’m glad I have the option to use the compounded product.
valerie said:
Mar 04, 10 at 9:34 amthe new NT is working better for me…first time ive seen my basal temp increase in over 9 months…l think the new stuff is an improvement!…Val
linda from scotland said:
Mar 05, 10 at 9:31 ami was sent my nature thyroid from the states over 2 weeks ago,and for some strange reason it has not yet arrived,in desperation,ilooked up a site selling generic armour-can anyone advise me on either of thes points or both?
Marion said:
Mar 11, 10 at 12:40 amI am on the new NT since two weeks and not feeling so great.Could it be that the FDA forces these companies to ad fillers that make Armour and NT not work well anymore so they will have a good reason to discontinue all of the natural Thyroid meds and force us to take the chemical ones which will cause so many other problems that we will end up having to take other meds to deal with all the new problems? Since Juli 09 I have been so sick and switched to 5 different meds, all natural thyroid from pigs or compoundet and nothing worked as well as the old Armour.
I have wanted to not live anymore if this is going to be how I feel for the rest of my life.Why can’t we get the old Armour back so we can feel great again?
Marie said:
Mar 11, 10 at 6:09 pmWhat is your thoughts of using Natures Source Natural Thyroid when I was on Armour Natural Thyroid for many years 2 gr. Now the Natural has the addition of Kelp and Adrenal Gland and Pituitary Gland…I am lactose intollerant and allergic to Milk and Penicylin and Erythromycin (if that means anything — not sure). I found that I could not get any thyroid medication at all from any pharmacy and was told to go to a compounding shop, but without insurance, it would cost me 4 X as much, so had no choice but to switch to Natural Thyroid. I mean, we are told never go without our thyroid and the pharmacy’s left us out in the cold. What kinds of problems are everyone experiencing…I have been achy and just plain awful…and distant and no sex drive. I had an accident that caused me to have near adreanal failure, so thought the adrenal support would be a good thing. Thoughts?
p lindsay said:
Mar 12, 10 at 11:57 ami have been on nature throid for over a year. switching for the better from armour. i recently got a new prescription sent to me for the new nature throid. it definitely is not working as good as the old nature throid and i am now experiencing symptoms of fatigue and cold. i tried taking a higher dose and it didnt make a bit of difference. not sure what to do now and it is very frustrating. i did email rlc labs and told them what i am experiencing. i think everyone should let them know if they are finding it isnt working as well for them.
valerie said:
Mar 20, 10 at 9:10 amgosh l hate to say this…ITS NOT WORKING…how do l know..cold…low temps…blah blah blah blah blah…we all know the drill…so here is another product that doesnt work…AND l do not believe the FDA is not behind it…thats 2 companies now and the only 2 we have..that have changed their product for the worse…what sane business person would ever do that on purpose…dont care what the FDA says…l live in California where the federal govt has turned the water off on thousands of farmers for over a year now…and are now extorting votes for the healthcare bill with a promise of turning it back on.…we are being blackmailed by our federal govt…so l do not believe the FDA…what is the first letter in their name…FEDERAL as in FEDERAL GOVT
(From Janie: it’s a toss up, as many other folks are reporting the new Naturethroid to work well once they get past the initial introduction in the use of Naturethroid and adjust their adrenal treatment, if needed, so hopefully it will take just a raise for you or cortisol if needed.)
p lindsay said:
Mar 23, 10 at 12:00 pmi am almost out of my old naturethroid pills which do work and will have to start taking my new batch again so we will see.
i emailed RLC labs with my concerns and i havent gotten a reply. it has been almost 2 weeks.
Libby said:
Apr 04, 10 at 9:02 pmAfter about 16 years of T4-only, switched to T3-only at the end of December 2009 due to an RT3 problem (take it sublingually). Just started to switch to dessicated thyroid and took my first Naturethroid (new formula) sublingually and it was “very” chalky, took a long time to dissolve (little over an hour), and didn’t completely dissolve. Not thrilled with it, but anything is better than the thought of going back to T4-only! Is the new Naturethroid supposed to be better than the old formula?
Priscilla said:
Apr 06, 10 at 1:09 amThe new NT is not working as well as the old. I guess I will have to use non-US meds from now on. I’m not looking forward to it.
Mila said:
Apr 20, 10 at 8:13 amI love this site and all of you. I am an NTH yahoo group veteran and have been googling my eyes out all morning trying to decide whether or not to leave ERFA for skin eruptions and go to Nature-throid — and ended up right here back at Janie’s LOL.
After not being able to reach Nature-throid (at all) yet was able to speak to someone at Erfa (AND a staff doctor is calling me back) — and reading all your posts, I have made the decision to stay put on the erfa and find some other skin remedies.
Have a wonderful week!
Hilary said:
Apr 25, 10 at 9:53 amWake Up and Smell the Reformulation! Holy Hypo. Temps plunging, hair falling out, brain fog, mood in the tank. What’s up? Oh, here’s a week old refill of my awesome Naturethroid. Hmmm…let’s Google reformulation. Bam, here I am. What, there’s no obligation for them to tell you the formula is changing? Just the old switcheroo, again! Boy, did I get into this natural thyroid game at the wrong time. After my DX, tried levo for one year until I switched to Armour. I had one month of feeling great on the Old Armour until my first refill of New Armour. Now this! I KNOW it’s the reformulated Naturethroid that’s not working for me. I had a small stash of Westhroid, and after taking them for one day, my recent stomach and IBS troubles went away along with all my other hypo symptoms. Too bad I only have a few more. Now it’s on to Erfa. I’m pissed, but hopeful. Thanks Janie and everyone for the scoop, which you can only find here.
Hilary said:
Apr 26, 10 at 1:33 pmUpdate: I ordered the Erfa from universaldrugstore.com ($20 for 100 60mg…I’m psyched!) AND compounded desiccated thyroid with acidophilus from Hook’s in Indiana. One of those HAS to work, right? Thank goodness I have a good doctor who let call in both RXs today! She’s also on natural thyroid (Armour) so she understands. New Armour was just OK for me but after the shortage when I started Naturethroid, it was a huge improvement…until last week when I got the reformulation. I take it orally in the a.m. then sublingual in the afternoon and although it dissolved just fine with a bit of sugar or sublingual B12, it wasn’t working at all for me. In the 4 months I was on Naturethroid (plus low carb, exercise, blah blah) I finally was able to lose 12 of the 25 pounds I gained when going hypo and I don’t want it back. So until I get my new RXs, I’m mortar and pestling my brains out to pulverize that evil cellulose and rotten little fillers. No offensive to those of you that are doing good on the new NT! Cheers to you! I wish I was too!
ellen said:
Apr 28, 10 at 10:30 amhi. i’m on the new armour, pulverizing etc, but what a pain! i like the zip in the am, and didn’t get that on Naturethroid, but my temps still low and tired in pm. Can we tell the compounding pharmacies what we want in the compound. If so, what would be the closest thing to the original armour? ellen
(From Janie: Erfa is the closest to the old Armour. Yes, you can tell compounders, via a doctors prescription, what you want. Just understand whether you are getting des. thyroid or synthetic T4 and T3. Ellen, are you sure you are on enough thyroid meds?)
Denice said:
Jun 18, 10 at 3:05 pmI went from synthroid to Naturthroid in Aug 2009, it took 3 months to get though it but seemed worth it — until I ran out of naturethroid and went on a compound — that caused all kinds of reactions, finally got the new naturethoid and my heart has been having all kinds of problems from racing to palptations. Working with doc to change dose, but the only thing that seems to help is to continue to add levo. I am about to give up on the naturethroid.
Anyone else having heart issues on the new naturethroid? Will crushing it stop the heart issues?
(From Janie: Yes, crushing it and adding a bit of honey or sugar definitely helps. See my other blog posts below this earlier this year. If you continue to have palps after a week of doing that, you either have low cortisol and/or low ferritin that needs discovery and treatment. Patient groups can help you: http://www.stopthethyroidmadness.com/talk-to-others Adding Levo is simply masking the problem and will make you worse down the line )
Barbara said:
Jul 11, 10 at 11:40 amWent on Armour thyroid meds after another doc put my on Synthroid and I had horrible symptoms appear. My new DO took me off the Synthroid and put me on Armour. (6 months or so) Started to feel fine but after a couple of months I went down hill again. One of the new things I noticed was a bout with swollen ankles, fatigue and a change in my urine color. Now I drink plenty of water so that isn’t it. She then took me off Armour and compounded my meds. Started to feel better but for the second time I had a bout of swollen ankles and fatigue. I just started the compounded meds a week ago so I do need to give them a chance. Has anyone had this, should I be getting my kidneys checked, heart?? I am so disheartened at this time.…..
(from Janie: you needed to be chewing up the Armour to release the desiccated thyroid from the excess cellulose – the latter which binds the thyroid. Doesn’t work well unless you do. Now that you are on compounded, you need to tell them NOT to use cellulose as a filler, but powdered acidolpholus. Also see if you are here: http://www.stopthethyroidmadness.com/mistakes-patients-make )
Suzanne said:
Jul 17, 10 at 2:01 pmHave been on Naturethroid for about 4 mos. after having compounded meds. Went off compounded meds because I seemed to be all over the place from one mo. to the next. The Naturethroid seemed to be working and then for the past 2 weeks I have been really fatigued, bad foot & ankle cramps, light-headed when standing up and headaches on a pretty regular basis. I go back to my dr. on Wed. but wanted to know it anyone else is having problems on Naturethorid.
(from Janie: you need to be chewing it up to release the desiccated thyroid from the cellulose filler. But you may need to be doing a 24 hour adrenal saliva test, as well.)
Suzanne said:
Jul 19, 10 at 10:15 amFor about a week I tried crushing it up and mixed w/honey under my tongue but felt kind of sick to my stomach after about 1/2 hr. Didn’t notice any real difference in energy and still had all the other symptoms.
I wrote in because I was curious if any one else felt good after switching and then a downturn after a few weeks. I am going to the dr on Wed but she is not into saliva testing or Naturethroid for that matter. She gives it to me because I request it. I have been to several drs in the area but have not found a dr that is knowledgeable about desiccated thyroid meds. I read this website and try to help myself from the other suggestions.
(From Janie: you order the saliva test yourself. I would. Also use this page: http://www.stopthethyroidmadness.com/mistakes-patients-make and get further feedback from other patients: http://www.stopthethyroidmadness.com/talk-to-others )
Pollie said:
Jul 29, 10 at 8:02 amRE: Suzanne, I have been on Nature-throid for a little over a month now. It worked great for the first couple of weeks. But , too, started having major foot, ankle, and joint cramps on it (so bad my doc had to prescribe me prednisone to reduce swelling). This has NEVER happened before. He thinks it’s the Nature-throid causing it: makes sense. I am really disheartened because I have tried almost EVERY thyroid med and this one is good, except for this debilitating side effect. Anyone know how to combat this? I want to stay on it because it makes my hair, skin, and overall mood great! Thanks.
(From Janie: you need to be chewing the Naturethroid up before swallowing to release the thyroid from the cellulose filler. And you may not be on enough. http://www.stopthethyroidmadness.com/mistakes-patients-make )