As the one grain tabs of Natu­reth­roid desic­ca­ted thy­roid by RLC Labs are hit­ting phar­macy shel­ves again all across the nation here and there after the recent shor­ta­ges and the sad refor­mu­la­tion of Armour,  and patients are star­ting to use the new Natu­reth­roid, we are gathe­ring some good infor­ma­tion, both anec­do­tal and factual:

  • The typi­cal smell of desic­ca­ted por­cine is less intense with the new tablets. We have no idea why.
  • The tablets are now stam­ped with RLC on one side, and N over 1 on the other, whe­reas before you’d see just NT1 or a refe­rence to the fact that Time Caps Labs (TCL) used to make Natu­reth­roid for RLC Labs
  • The pac­kage insert is no lon­ger inside the bottle but stuck on top of the cap
  • Lot num­ber info used to be on the edge of the label run­ning ver­ti­cally, whe­reas now, it runs along the bot­tom of the label  under the ingredients.

One grain is still 65 mg, with the T3 con­tent being at 9 mcg and the T4 con­tent being at 38 mcg.  The T2, T1 and cal­ci­to­nin still unmeasured.

There are filler/inactive ingre­dients which have changed:

  • Cal­cium filler has moved up from 16 mg to 17 mg (cal­cium binds thy­roid, but you just take more. Don’t swa­llow it with milk, please.)
  • The old con­tai­ned Mag­ne­sium, Potas­sium, and Sodium (each at less than 1 mg), whe­reas in the new, potas­sium is now removed
  • And here’s the best part: the old NT had Hydro­propyl Methylcellu­lose – that’s the lar­ger size cellu­lose struc­ture which we know binds some of the thy­roid hor­mo­nes. Now, the new NT has Microcrys­ta­line Cellu­lose, the sma­ller size. (Too bad we can’t see all cellu­lose removed!)

Below are the new NT fillers, which are iden­ti­cal to the old except for the cellu­lose change:

Car­naba Wax, Colloi­dal Sili­con Dio­xide, Dical­cium Phosphate, Hypro­me­llose, Lac­tose Monohy­drate, Mag­ne­sium Stea­rate, Mic­rocrys­ta­line Cellu­lose, Pol­yethy­lene Gly­col (PEG)-400, Sodium Starch Gly­co­late, Stea­ric Acid.

Most all the above comes cour­tesy of Stepha­nie Buist, owner of the Iodine group on Yahoo and thy­roid and adre­nal patient and advo­cate.  Thank you, Steph!  You can read about the fillers here by scro­lling down.

Oh and by the way, the new tablets are now sco­red. A help­ful addition!

In patient groups, we are seeing a variety of expe­rien­ces with the new Natu­reth­roid.  Most folks seem happy with it so far, and even some report it seems a tad stron­ger than the old (the cellu­lose change may have cau­sed that). Occa­sio­nally, someone will report pro­blems, but they appear to be from under­do­sing or a poten­tial RT3 pro­blem which has ari­sen and needs treat­ment with T3-only.  Chan­ging brands can also bring dif­fe­rent reac­tions, so you have to wig­gle the dosage around some­ti­mes to find your sweet spot once again.

All in all, it looks good.

P.S. If you are rea­ding this via the News­let­ter Noti­fi­ca­tion, just click on the above link to put your­self right on the actual blog post if you want to com­ment. Let’s gather all our expe­rien­ces with the new Naturethroid.

********************************************

If you mis­sed the last inter­net radio Thy­roid Patient Com­mu­nity Call with Dr. Kent Hol­torf, you mis­sed a VERY good one. Thank you Dr. Hol­torf for exce­llent infor­ma­tion. But good news! All the shows are recor­ded.  Just go to the follo­wing link, scroll down, and you can click on any past inter­views, inc­lu­ding two with Dr.  John C. Lowe and a great one with Endoc­ri­no­lo­gist Dr Pep­per – one of a rare breed of open-minded Endos.  (I’ve also stop­ped doing my long intro’s about me in the last two, figu­ring if someone wants to know, they can go to the About Me page, or read the Intro­duc­tion in the book which has even more detail. lol.)

http://www.talkshoe.com/talkshoe/web/talkCast.jsp?masterId=62603&cmd=tc


  • Want to keep track of these “fringe web­site” blog posts? ;-) Curious what’s on Janie’s mind? Use the noti­fi­ca­tion on the lower left of the links, called a News­let­ter, or an RSS Feed.
  • The extre­mely hip and sophis­ti­ca­ted STTM t-shirts are half price! Great BUMPER STICKERS, too. Spread the word – YOU may make a dif­fe­rence in someone’s life.
  • Check out the patient-to-patient book with even more detail (and which doc­tors seem to res­pect more than websites).
  • Need to unders­tand all your best options for thy­roid treat­ment? Go here.
  • Keep infor­med of each live Thy­roid Patient Com­mu­nity Call on Talkshoe by sig­ning up as a follo­wer.

27 Responses to “Here’s the skinny about the “new” Naturethroid: the good, the bad, and the curious”

  1. Jan said:

    Feb 20, 10 at 3:49 pm

    So basicly what you are sying is that Nature-Throid has also been reformulated?

    (From Janie: perhaps, but not with the nega­tive con­no­ta­tion that we got with Armour)

  2. Michele said:

    Feb 20, 10 at 5:09 pm

    After fin­ding Armore was chan­ged (and due to shor­ta­ges) I had a month or two on Natu­reth­roid which was great…had to go to new Armore for a month…and felt myself go slowly down hill…and just got Natu­reth­roid again. I have to say I’ve been sur­pri­sed at it not wor­king as well as before…thought… something is dif­fe­rent I think…I seem to need more…will see how that goes…pleeeeassse!

  3. Carol G. said:

    Feb 20, 10 at 6:30 pm

    I see in the ingre­dients that there is lac­tose monohy­drate in Natu­reth­roid. From what I could find it appears that is a milk deri­va­tive. Being aller­gic to milk pro­ducts I always have to won­der why they would put milk deri­va­tive in medi­cine?? I did bet­ter on Natu­reth­roid than the new Armour but still not near as good as I did on the old Armour. Now I’m on com­poun­ded and aching all over…after rea­ding this I’m thin­king I need to find out what they are put­ting as filler in my com­poun­ded. Thanks for the infor­ma­tion it’s been very helpful.

  4. annie phenix said:

    Feb 20, 10 at 8:27 pm

    I haven’t done well on Natu­reth­roid since I switched from the new Armour last sum­mer. I had seve­ral hypo symp­toms come back

    I am now trying com­poun­ded Armour and so far so good. The only filler the phar­macy put in was aci­dopho­lis. I am sick to read that the makers of Natu­re­troid put a milk deri­va­tive in it as I can’t have milk/caseins either. Maybe that is why I haven’t done well on Natu­reth­roid? I very much appre­ciate your poin­ting that out, Carol G.

  5. Lethal Lee said:

    Feb 21, 10 at 5:40 am

    (From Janie: Hi Lethal. I think you mis­read the infor­ma­tion. They state they only switched from methyl to micro, not inc­rea­sed it. But it’s too bad that any has to be in there at all. Agreed.)

    Mic­rocrys­ta­line Cellu­lose is also the SAME type of cellu­lose that is in in Armour.

    The recent Armour refor­mu­la­tion redu­ced Dex­trose & INCREASED the Mic­rocrys­ta­line Cellu­lose con­tent and THAT cau­sed all the pro­blems we are all well aware of.

    Why then is the Mic­rocrys­ta­line Cellu­lose in the NT any dif­fe­rent? Why would they inc­rease Cellu­lose at all when they are aware of the Armour fiasco?
    http://www.stopthethyroidmadness.com/2009/11/11/is-cellulose-the-real-problem/
    See blog

    One per­son has com­men­ted that new NT is chal­kier & you say it smells less piggy too. Doesnt this sound just like the com­ments made for new Armour?

    Avi­cel is a brand of Mic­rocrys­ta­line Cellu­lose & is often used in the com­poun­ded NTH (cer­tainly the case in Aus­tra­lia). That is cer­tainly problematic.

    In fact on RTH we are advi­sing folks to avoid cellu­lose of any kind. Much bet­ter to have Aci­dophi­lus for example.

    As far as Lac­tose goes ALL NTH meds inc­lu­ding com­poun­ded, con­tain trace amounts of it. It is in the Thy­roid USP pow­der itself.

    See..

    ■Lac­tose Monohy­drate — tra­cea­ble amount as part of desic­ca­ted thy­roid pow­der USP
    http://www.stopthethyroidmadness.com/armour-vs-other-brands/

  6. Sally said:

    Feb 21, 10 at 11:42 am

    Am just star­ting on com­poun­ded and they switched filler for me to bio­fla­vi­noid. Hoping it works well and i will feel well.
    Did not know about the trace Lac­tose in Thy­roid USP pow­der.
    All very inte­res­ting. THank you!

  7. Jenny said:

    Feb 21, 10 at 7:02 pm

    So is lac­tose added as a filler a pro­blem or not? I just called my com­poun­ding phar­macy, and they said they don’t add cellu­lose but use lac­tose as the filler. They argued that there was abso­lu­tely no pro­blem with lac­tose as a filler. Does it bind with the thyroid?

  8. Meg said:

    Feb 22, 10 at 4:30 am

    @Sally
    As com­poun­ded has recently become an option in Nor­way (alliance apo­tek), I’m inte­res­ted in fillers.
    Do you know what it is, the bio­fla­vi­noid your far­macy is using?
    Thanks!
    :) meg

  9. Nickie said:

    Feb 22, 10 at 9:09 am

    I was only on Nature-throid for a short time but I didn’t see too much of a dif­fe­rence but have tal­ked to someone who had really bad side effects and actually felt worse than she did before she star­ted on Armour — said all her symp­toms came back. She is now on the com­poun­ded des­si­ca­ted thy­roid and had a pro­blem adjus­ting to that for the first week and now doing great. Maybe it’s just that the body has to get adjus­ted to the new thy­roid sup­ple­ment. I am doing much bet­ter on the natu­ral des­si­ca­ted thy­roid from the com­poun­ding phar­macy than I did on the Nature-throid and I’m also aller­gic to cow milk so I’m glad I have the option to use the com­poun­ded product.

  10. valerie said:

    Mar 04, 10 at 9:34 am

    the new NT is wor­king bet­ter for me…first time ive seen my basal temp inc­rease in over 9 months…l think the new stuff is an improvement!…Val

  11. linda from scotland said:

    Mar 05, 10 at 9:31 am

    i was sent my nature thy­roid from the sta­tes over 2 weeks ago,and for some strange rea­son it has not yet arrived,in desperation,ilooked up a site selling gene­ric armour-can anyone advise me on either of thes points or both?

  12. Marion said:

    Mar 11, 10 at 12:40 am

    I am on the new NT since two weeks and not fee­ling so great.Could it be that the FDA for­ces these com­pa­nies to ad fillers that make Armour and NT not work well any­more so they will have a good rea­son to dis­con­ti­nue all of the natu­ral Thy­roid meds and force us to take the che­mi­cal ones which will cause so many other pro­blems that we will end up having to take other meds to deal with all the new pro­blems? Since Juli 09 I have been so sick and switched to 5 dif­fe­rent meds, all natu­ral thy­roid from pigs or com­poun­det and nothing wor­ked as well as the old Armour.
    I have wan­ted to not live any­more if this is going to be how I feel for the rest of my life.Why can’t we get the old Armour back so we can feel great again?

  13. Marie said:

    Mar 11, 10 at 6:09 pm

    What is your thoughts of using Natu­res Source Natu­ral Thy­roid when I was on Armour Natu­ral Thy­roid for many years 2 gr. Now the Natu­ral has the addi­tion of Kelp and Adre­nal Gland and Pitui­tary Gland…I am lac­tose into­lle­rant and aller­gic to Milk and Penicy­lin and Eryth­romy­cin (if that means anything — not sure). I found that I could not get any thy­roid medi­ca­tion at all from any phar­macy and was told to go to a com­poun­ding shop, but without insu­rance, it would cost me 4 X as much, so had no choice but to switch to Natu­ral Thy­roid. I mean, we are told never go without our thy­roid and the pharmacy’s left us out in the cold. What kinds of pro­blems are ever­yone experiencing…I have been achy and just plain awful…and dis­tant and no sex drive. I had an acci­dent that cau­sed me to have near adrea­nal fai­lure, so thought the adre­nal sup­port would be a good thing. Thoughts?

  14. p lindsay said:

    Mar 12, 10 at 11:57 am

    i have been on nature throid for over a year. switching for the bet­ter from armour. i recently got a new presc­rip­tion sent to me for the new nature throid. it defi­ni­tely is not wor­king as good as the old nature throid and i am now expe­rien­cing symp­toms of fati­gue and cold. i tried taking a higher dose and it didnt make a bit of dif­fe­rence. not sure what to do now and it is very frus­tra­ting. i did email rlc labs and told them what i am expe­rien­cing. i think ever­yone should let them know if they are fin­ding it isnt wor­king as well for them.

  15. valerie said:

    Mar 20, 10 at 9:10 am

    gosh l hate to say this…ITS NOT WORKING…how do l know..cold…low temps…blah blah blah blah blah…we all know the drill…so here is another pro­duct that doesnt work…AND l do not believe the FDA is not behind it…thats 2 com­pa­nies now and the only 2 we have..that have chan­ged their pro­duct for the worse…what sane busi­ness per­son would ever do that on purpose…dont care what the FDA says…l live in Cali­for­nia where the fede­ral govt has tur­ned the water off on thou­sands of far­mers for over a year now…and are now extor­ting votes for the health­care bill with a pro­mise of tur­ning it back on.…we are being black­mai­led by our fede­ral govt…so l do not believe the FDA…what is the first let­ter in their name…FEDERAL as in FEDERAL GOVT

    (From Janie: it’s a toss up, as many other folks are repor­ting the new Natu­reth­roid to work well once they get past the ini­tial intro­duc­tion in the use of Natu­reth­roid and adjust their adre­nal treat­ment, if nee­ded, so hope­fully it will take just a raise for you or cor­ti­sol if needed.)

  16. p lindsay said:

    Mar 23, 10 at 12:00 pm

    i am almost out of my old natu­reth­roid pills which do work and will have to start taking my new batch again so we will see.
    i emai­led RLC labs with my con­cerns and i havent got­ten a reply. it has been almost 2 weeks.

  17. Libby said:

    Apr 04, 10 at 9:02 pm

    After about 16 years of T4-only, switched to T3-only at the end of Decem­ber 2009 due to an RT3 pro­blem (take it sublin­gually). Just star­ted to switch to des­si­ca­ted thy­roid and took my first Natu­reth­roid (new for­mula) sublin­gually and it was “very” chalky, took a long time to dis­solve (little over an hour), and didn’t com­ple­tely dis­solve. Not thri­lled with it, but anything is bet­ter than the thought of going back to T4-only! Is the new Natu­reth­roid sup­po­sed to be bet­ter than the old formula?

  18. Priscilla said:

    Apr 06, 10 at 1:09 am

    The new NT is not wor­king as well as the old. I guess I will have to use non-US meds from now on. I’m not loo­king for­ward to it.

  19. Mila said:

    Apr 20, 10 at 8:13 am

    I love this site and all of you. I am an NTH yahoo group vete­ran and have been goo­gling my eyes out all mor­ning trying to decide whether or not to leave ERFA for skin erup­tions and go to Nature-throid — and ended up right here back at Janie’s LOL.
    After not being able to reach Nature-throid (at all) yet was able to speak to someone at Erfa (AND a staff doc­tor is calling me back) — and rea­ding all your posts, I have made the deci­sion to stay put on the erfa and find some other skin reme­dies.
    Have a won­der­ful week!

  20. Hilary said:

    Apr 25, 10 at 9:53 am

    Wake Up and Smell the Refor­mu­la­tion! Holy Hypo. Temps plun­ging, hair falling out, brain fog, mood in the tank. What’s up? Oh, here’s a week old refill of my awe­some Natu­reth­roid. Hmmm…let’s Goo­gle refor­mu­la­tion. Bam, here I am. What, there’s no obli­ga­tion for them to tell you the for­mula is chan­ging? Just the old switche­roo, again! Boy, did I get into this natu­ral thy­roid game at the wrong time. After my DX, tried levo for one year until I switched to Armour. I had one month of fee­ling great on the Old Armour until my first refill of New Armour. Now this! I KNOW it’s the refor­mu­la­ted Natu­reth­roid that’s not wor­king for me. I had a small stash of Westh­roid, and after taking them for one day, my recent sto­mach and IBS trou­bles went away along with all my other hypo symp­toms. Too bad I only have a few more. Now it’s on to Erfa. I’m pis­sed, but hope­ful. Thanks Janie and ever­yone for the scoop, which you can only find here.

  21. Hilary said:

    Apr 26, 10 at 1:33 pm

    Update: I orde­red the Erfa from universaldrugstore.com ($20 for 100 60mg…I’m psyched!) AND com­poun­ded desic­ca­ted thy­roid with aci­dophi­lus from Hook’s in Indiana. One of those HAS to work, right? Thank good­ness I have a good doc­tor who let call in both RXs today! She’s also on natu­ral thy­roid (Armour) so she unders­tands. New Armour was just OK for me but after the shor­tage when I star­ted Natu­reth­roid, it was a huge improvement…until last week when I got the refor­mu­la­tion. I take it orally in the a.m. then sublin­gual in the after­noon and although it dis­sol­ved just fine with a bit of sugar or sublin­gual B12, it wasn’t wor­king at all for me. In the 4 months I was on Natu­reth­roid (plus low carb, exer­cise, blah blah) I finally was able to lose 12 of the 25 pounds I gai­ned when going hypo and I don’t want it back. So until I get my new RXs, I’m mor­tar and pest­ling my brains out to pul­ve­rize that evil cellu­lose and rot­ten little fillers. No offen­sive to those of you that are doing good on the new NT! Cheers to you! I wish I was too!

  22. ellen said:

    Apr 28, 10 at 10:30 am

    hi. i’m on the new armour, pul­ve­ri­zing etc, but what a pain! i like the zip in the am, and didn’t get that on Natu­reth­roid, but my temps still low and tired in pm. Can we tell the com­poun­ding phar­ma­cies what we want in the com­pound. If so, what would be the clo­sest thing to the ori­gi­nal armour? ellen

    (From Janie: Erfa is the clo­sest to the old Armour. Yes, you can tell com­poun­ders, via a doc­tors presc­rip­tion, what you want. Just unders­tand whether you are get­ting des. thy­roid or synthe­tic T4 and T3. Ellen, are you sure you are on enough thy­roid meds?)

  23. Denice said:

    Jun 18, 10 at 3:05 pm

    I went from synth­roid to Naturth­roid in Aug 2009, it took 3 months to get though it but see­med worth it — until I ran out of natu­reth­roid and went on a com­pound — that cau­sed all kinds of reac­tions, finally got the new natu­rethoid and my heart has been having all kinds of pro­blems from racing to palp­ta­tions. Wor­king with doc to change dose, but the only thing that seems to help is to con­ti­nue to add levo. I am about to give up on the natu­reth­roid.
    Anyone else having heart issues on the new natu­reth­roid? Will crushing it stop the heart issues?

    (From Janie: Yes, crushing it and adding a bit of honey or sugar defi­ni­tely helps. See my other blog posts below this ear­lier this year. If you con­ti­nue to have palps after a week of doing that, you either have low cor­ti­sol and/or low ferri­tin that needs dis­co­very and treat­ment. Patient groups can help you: http://www.stopthethyroidmadness.com/talk-to-others Adding Levo is simply mas­king the pro­blem and will make you worse down the line )

  24. Barbara said:

    Jul 11, 10 at 11:40 am

    Went on Armour thy­roid meds after another doc put my on Synth­roid and I had horri­ble symp­toms appear. My new DO took me off the Synth­roid and put me on Armour. (6 months or so) Star­ted to feel fine but after a cou­ple of months I went down hill again. One of the new things I noti­ced was a bout with swo­llen ankles, fati­gue and a change in my urine color. Now I drink plenty of water so that isn’t it. She then took me off Armour and com­poun­ded my meds. Star­ted to feel bet­ter but for the second time I had a bout of swo­llen ankles and fati­gue. I just star­ted the com­poun­ded meds a week ago so I do need to give them a chance. Has anyone had this, should I be get­ting my kid­neys chec­ked, heart?? I am so dishear­te­ned at this time.…..

    (from Janie: you nee­ded to be che­wing up the Armour to release the desic­ca­ted thy­roid from the excess cellu­lose – the lat­ter which binds the thy­roid. Doesn’t work well unless you do. Now that you are on com­poun­ded, you need to tell them NOT to use cellu­lose as a filler, but pow­de­red aci­dolpho­lus. Also see if you are here: http://www.stopthethyroidmadness.com/mistakes-patients-make )

  25. Suzanne said:

    Jul 17, 10 at 2:01 pm

    Have been on Natu­reth­roid for about 4 mos. after having com­poun­ded meds. Went off com­poun­ded meds because I see­med to be all over the place from one mo. to the next. The Natu­reth­roid see­med to be wor­king and then for the past 2 weeks I have been really fati­gued, bad foot & ankle cramps, light-headed when stan­ding up and hea­daches on a pretty regu­lar basis. I go back to my dr. on Wed. but wan­ted to know it anyone else is having pro­blems on Naturethorid.

    (from Janie: you need to be che­wing it up to release the desic­ca­ted thy­roid from the cellu­lose filler. But you may need to be doing a 24 hour adre­nal saliva test, as well.)

  26. Suzanne said:

    Jul 19, 10 at 10:15 am

    For about a week I tried crushing it up and mixed w/honey under my ton­gue but felt kind of sick to my sto­mach after about 1/2 hr. Didn’t notice any real dif­fe­rence in energy and still had all the other symp­toms.
    I wrote in because I was curious if any one else felt good after switching and then a down­turn after a few weeks. I am going to the dr on Wed but she is not into saliva tes­ting or Natu­reth­roid for that mat­ter. She gives it to me because I request it. I have been to seve­ral drs in the area but have not found a dr that is know­led­gea­ble about desic­ca­ted thy­roid meds. I read this web­site and try to help myself from the other suggestions.

    (From Janie: you order the saliva test your­self. I would. Also use this page: http://www.stopthethyroidmadness.com/mistakes-patients-make and get further feed­back from other patients: http://www.stopthethyroidmadness.com/talk-to-others )

  27. Pollie said:

    Jul 29, 10 at 8:02 am

    RE: Suzanne, I have been on Nature-throid for a little over a month now. It wor­ked great for the first cou­ple of weeks. But , too, star­ted having major foot, ankle, and joint cramps on it (so bad my doc had to presc­ribe me pred­ni­sone to reduce swe­lling). This has NEVER hap­pe­ned before. He thinks it’s the Nature-throid cau­sing it: makes sense. I am really dishear­te­ned because I have tried almost EVERY thy­roid med and this one is good, except for this debi­li­ta­ting side effect. Anyone know how to com­bat this? I want to stay on it because it makes my hair, skin, and ove­rall mood great! Thanks.

    (From Janie: you need to be che­wing the Natu­reth­roid up before swa­llo­wing to release the thy­roid from the cellu­lose filler. And you may not be on enough. http://www.stopthethyroidmadness.com/mistakes-patients-make )


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