More on Acella desiccated thyroid….plus RT3 ratio calculator fine tuned!

Yesterday, I had a friendly and informative conversation with Philip Vogt, the President of Acella Pharmaceuticals, and Ellen Gettenberg, Director of Marketing.   Acella is the company which brought out a generic form of desiccated thyroid, and which first caught the eye of thyroid patients in November, 2010.  And I want to pass onto you what I learned:

Acella is different: Acella Pharmaceutical is not like the gigantic pharms we often hear about. Instead, they attempt to target the under-served markets, producing medications for particular niches of treatment, or those which are low-profile medications.  They also seek to produce lower-priced competitive versions of certain medications while keeping the quality.

How they make their version of desiccated thyroid: When it specifically comes to its desiccated thyroid, they go by older version “recipes” – using more dextrose (sugar) and less methylcellulose.  But in their case, the tablets are stated to contain NO cellulose.  That is actually good.  Their tablets are also not as hard-pressed as Armour seems to be now. I’d love to hear from folks who’ve been on Acella if they have tried to it sublingually, and what the results were.

The ingredients: Acella does a 65 mg tablet (update: this is now 60 mg).  The desiccated thyroid is speculated to come from the same manufactured source as do Armour and Naturethroid. Each 65 mg grain contains 38 mg T4 and 9 mcg T3 (plus unmeasured amounts of T2, T1 and calcitonin). The inactive ingredients are calcium stearate, dextrose monohydrate, maltodextrin and mineral oil.


ABOUT THE RT3 ONLINE CALCULATOR on STTM: My brainy techs have added three more combinations to the calculator, so it is now ready-to-go to help you figure out your ratio: So far, the feedback is very positive and we have seemed to remove all kinks. REMEMBER: you need to put your Free T3/total T3 in first, then all the measurements will appear for the RT3.

WHEN TESTING YOUR THYROID LEVELS: remember NOT to take your desiccated thyroid, or your T3-only, before labs. The T3 rises consistently after you take it, giving you false-high reading and freaking your clueless doctor out.  **Picture doctor, eyes bugged out like a giant wasp, looking at lab result** With desiccated thyroid, the T3 will peak in approx. 2 hours; with T3-only, it can take approx 4 hours to peak.  Recommend labwork found here.

NEED A GOOD PATIENT GROUP OR ONE-ON-ONE CONSULTATION? Go here.  Of course, the groups are free and can be very helpful. Or, you can choose a paid consultation with Janie, which seems to be extremely helpful for those who want more immediate feedback and help.

TYPICAL QUESTIONS AND ANSWERS about thyroid, treatment, more issues:

91 Responses to “More on Acella desiccated thyroid….plus RT3 ratio calculator fine tuned!”

  1. Shauna

    I don’t know about the other pharmacies, but with Walgreens you really have to go through a few hoops to get it. You call their ON-LINE number (877-250-5823) and specifically ask for NP thyroid by Acella. Just to make sure, I emphasized that it is NOT Armour thyroid. The NP thyroid by Acella is NOT listed in their line up of products on the site (weird huh?) You have to request it. Then there is a funny process you have to go through to get it to your local pharmacy. But on the upside, it is easier the next time! Good Luck!

  2. Laura Fleckenstein

    Jewel Osco and Marianos in Chicago area have it available within one day of request.

  3. David

    I’ve been getting 60 mg tablets of NP Thyroid from my local Publix without any problem. Oddly enough my insurance company classifies 30 mg as a T1 drug and 60 & 90 mg as T3. And my copay due to an increase from Acella just went from $14 to $26 in one month. Anyone have any idea why the dramatic price increase?

  4. Krista

    I started taking Armour a few months after switching from Levothyroxin. When I went in for a recent refill, my pharmacy gave me NP Thyroid without even asking me. I made them change it back to Armour. Not sure why they decided to change. It was more expensive…so maybe??

    • Joan Fitler

      Actually the Thyroid Np is a very good med…for me anyway. I took Armour for awhile and all of a sudden it stopped working for me so now its Thyroid NP by Acella :)

    • Anna


      Have you been doing fine on Armour? I have been considering switching to it if I cannot get Acella, but most people seem unhappy with Armour these days…?

  5. Tammy

    I switched to Acella since Erfa is dealing with reformulation problems. I have been taking Acella for almost 2 months so far. I’m not having any problems taking it sublingually. They did not have Acella at any of the pharmacies where I live. I called my doctor & told them of the Erfa problem & I needed to find something else to take & I wanted to try Acella. The doctors office sent CVS pharmacy a script for the Acella. CVS ordered it & had it the next day. I paid $20 co-pay for 180 90 mg tablets, over a 90 day supply. I take 1 1/2 pills per day. I was paying $80 for 500 Erfa Thyroid tablets & it went up to $175. I would imagine the price increase has something to do with the porcine virus that ended up with millions of pigs slaughtered & another reason would be greed of course. I like the NP so I’m sticking with it.

  6. Cathy Poland

    How can I get Acella desiccated thyroid in Canada?

  7. Anna

    Still no news on the alledged reformulation of Erfa? I find it so strange that the company cannot find out what is wrong with it, or at least admit something seems to be wrong…I got a 500 ct bottle of 125 mg pills which made me feel like I had taken nothing all…all hypo symptoms returned with a vengeance.

  8. Cathy Poland

    I live in Canada, have been taking Erfa for years. I just started on a new batch and don’t feel very good. I’d like to get something from the US but don’t know how to get it as I need a US MD prescription. Help!

  9. Sonia Tolson

    CVS did not have the 60 mg in stock and has told me they are on back order from Acella. They haven’t heard anything else from Acella. They called around to all the CVS in Tucson and it was the same at all of them, they were out of stock. =(

  10. Rosemary Archer

    I live in a small rural community. I read so many good reviews on NP thyroid that I requested my doctor to switch me from Synthroid to NP thyroid. I have been taking the 60 MG of NP thyroid for approximately 6 months. It was time to increase the NP dosage (which we know I would) but my pharmacy told me that the 90 MG is on back order. Now I read from other people that CVC are saying that the 60 MG is on back order. Hope it is truly just a big demand and nothing more going on that has put the product in a shortage situation.

  11. Laray


    Does anyone out there have any clues as to why my thyroid medicine stopped working? It appears to be in my blood but not my cells. I was on compounded T3 for 7 years and apparently was told that the T3 receptors can burn out. I tried Nutri Meds porcine Glandular a few months later and it worked! However, I was allergic to it. Eight months later I was cleared of the allergy through N.A.E.T. so I went back on it with no side effects; however, it stopped working too! I am now taking WP Thyroid 2 grains or more and my eyebrows have not grown back and I still have a very sluggish metabolism and insomnia. In Feb. 2014 the T3 only stopped working within ONE week. I did not do anything drastic nor did I lose blood. I still can’t figure it out. It’s almost like people with diabetes when insulin doesn’t get into the cells only the T3 remains in my blood and I believe is not getting into my cells. HELP ANYONE? Does ANYONE have any clues as to what I need to do? ~Laray

  12. Irmajean Gaines

    I have taken Armour Thyroid 1/2 gr (30mg) for a number of years after a partial thyroidectomy in 1976. I did great on it until about 3-4 years ago when Armour changed their formula. I have taken the thyroid from Acella now for sometime and I do as well as I use to do on Armour. I have switched back and forth between the Armour and the one from Acella and I definitely do better on the Acella brand. I asked for generic Armour and they said they didn’t have it and the Acella is what they gave me. I like it better. Actually, my feet started tingling and it seems to do it more often when I am taking Armour. They don’t tingle as much when I am taking the Acella, in fact, none. SOOOOOOOO…..I guess I am trying to say, I am doing fine on it. Just my
    take, from my experience……!! It is much cheaper also!!

  13. Paige

    I’ve been taking NP thyroid by Acella for almost a year now and I like it very much, better than any other thyroid med I’ve taken. I took Levoxyl for many years and wanted to change to natural thyroid but was afraid of the change because of how sensitive my thyroid is to ANY change. But when Levoxyl disappeared I took the plunge. I got the info about NP thyroid from Stop the Thyroid Madness. I do take the NP thyroid sublingually every morning and I am quite happy with it. What it’s done is send my T3 up into good, normal ranges without taking anything other than the NP thyroid, whereas for many years I was taking an expensive compounded bioidentical T3 that just stopped working one day and sent me into a scary hyperthyroid state.

    I highly recommend NP Thyroid by Acella. Problem is, I went to my pharmacy today and they said the 90 mg I take is backordered. No real info on why. Does anyone have any reliable information about this?

  14. Jim

    I started my sad thyroid journey on Levothyroxine prescribed by a doctor who refused to prescribe a natural alternative. I never wanted to start on synthetic, but she wouldn’t listen. I found another doc who typically prescribed Armour. He was knowledgeable about the formula change. He said his patients initially had some problems but he resolved with a dosage change. I still requested NP by Acella as it sounded like the old Armour, and it paid off for me. I’m doing MUCH better. I contacted Acella and asked how they’re doing as a company and if there was anything I could do personally to help their business grow. I was told business is good and to basically keep using the product. NO problem!

  15. nomorebadnews!

    Any news on the situation with inadequate Acella and the so called shortage or back-ordered NP? I just found out-through another patient-that Erfa is going bad all of a sudden, like Armour did back in 2008. Oh the joys of being stuck in a rut of non functional medicine, and the nightmare of being ‘just another thyroid patient’-yes this is the end of my life part two…I really do feel like I am dying a slow death. I have been taking Erfa all this past year, as I felt it was definitely the best option for me, and after having issues with Acella’s shortages way back in 2013, I feared the worst, and went back on Erfa!

    Well then, I suppose my mental, and physical (chronic infections since May 2014) break down this past year all makes sense now (in part) since Erfa decided to be sneaky, as there is obviously something really wrong with their product, and everyone is talking about it again..This is really sad. And I am only one person out of thousands of other patients!! What gives?

    So, here’s my problem; is there still the issue of shortages with Acella’s NP, and if so, what would be a good sub? Would WP be worth it, or Nature-thyroid? I did really, really well on NP the year of 2011-2013 and a half, but the issue of the shortages was absolutely NOT something I wanted to chance. I took Nature Thyroid before Acella, and did not feel it was working well..although I’ve heard the conversion is slightly less potent? I don’t know..What can I say? Is there anyone out there who does well on WP, or Nature Thyroid? Or does anyone know about the back order issue at Acella? Seriously this is all too much. Can someone please keep this dialogue going..? Are there really shortages, are there back orders nationwide or what? Are there any ANY brands that can help us, and manufacture and deliver a quality and therapeutic hormone replacement? This whole business is really getting to me….what a mess.

    • Janie Bowthorpe

      Erfa was only bad last year. Patients are reporting doing better on it this year i.e. last years batches ran out. As far as others, it’s really individual what NDT you want to take. Some swear by Armour; others swear by WP or NP, etc. Acella’s NP-Thyroid has been reported easily gotten.

  16. Lisa

    i switched from Synthroid to Acella Thyroid in December 2014. My thyroid levels were good but I was experiencing hair loss which I blamed on the Synthroid. I wanted to go back on Armour Thyroid which I had taken previously with good results. Insurance wouldn’t approve Armour due to cost so I was given Acella Thyroid instead. This medicine is awfull!! My hairloss has gone from bad to horrible. I lose handfuls every day, much worse than I was on Synthroid. My levels hormone levels went from stable to all screwed up. My T3,is at top of range but T4 is at very bottom. TSH keeps rising. The only reason I am still on this drug is that I managed to get pregnant a few months after starting it (that fact is the only redeeming thing I will say about this drug). I am still losing handfuls of hair daily even though I am 5 months pregnant and should be experiencing fuller hair. My son is due Dec 3 2015 and I will be going back on Synthroid the day he comes out. If you are thinking about going on Acella thyroid and having hairloss, I strongly recommend you find something else. This medicine is making me go bald!

  17. Carol Chase

    I had a total thyroidectomy in March 2013 and was one levothyroxine for 6 months. During that time my hands and feet started to go numb and I had pretty bad joint pain. The doctor sent me to a osteo Dr and he said I needed surgery for carpel tunnel. I refused and asked my Endo to put me on Armour which fixed all the neurological problems, weight gain, and tiredness. I was on Armour for 1.5 years (at $50.00 month). I wanted to try Acella NP Thyroid because everyone said it worked great and is much less expensive ($10.00 month). I have been on it for 6 months and the neurological problems/joint pain are coming back as is the weight gain. I really want to switch back to Amour but it is so expensive. Is there anything else I can do to get the Acella to work better. I am taking 60 mg 2 x day.


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