Iso­Cort is a popu­lar over-the-counter cor­ti­sol sup­ple­ment with patients. It’s adver­ti­sed as pro­vi­ding a stan­dar­di­zed, sta­ble, and “gentle” dose of the adreno-cortical subs­tance Cor­ti­sol. Accor­ding to the com­pany that makes them, each tablet pro­vi­des 2 1/2 mg. of cor­ti­sol (**See below), and patients can bet­ter regu­late how much they need and when. 

Ingre­dients of Iso­cort are lis­ted are as follows: All com­pounds wildc­raf­ted or orga­ni­cally grown. Freeze-Dried Adre­nal Cor­tex (solu­ble frac­tio­na­tion) from New Zea­land Sheep. Echi­na­cea Extract (trace amount). Pru­nus and Loma­tium dis­sec­tum root iso­late (kreb concentrate-2%) in pellet base of lac­tose and lac­tase. A favo­rite place to order Iso­cort is www.vitaminmd.com, among others.

Iso­cort may be a fine pro­duct to start on if you simply want to sup­port your healthy adre­nals during stress­ful times, or if your adre­nal fati­gue is quite mild. If you have a more serious pro­blem with flag­ging adre­nals, most patients state that using HC (aka Hydro­cor­ti­sone, cor­ti­sol or brand name Cor­tef, which is by presc­rip­tion), an oral synthe­tic cor­ti­cos­te­roid, wor­ked far bet­ter for them. So you’ll want to con­si­der that switch even­tually after you have star­ted on Isocort. 

Addi­tio­nally, the Echi­na­cea may not be an extract you want to be on long term, though short term may be fine. PDF article here.

**We are sus­pi­cious that each tablet does NOT con­tain 2 1/2 mg cor­ti­sol. When someone on 8 tablets of Iso­cort (which should be 20 mgs. cor­ti­sol if you do your math) switched to 15 mgs HC, the 15 mg HC was FAR more potent!

Bot­tom line…though we think it’s fine to start on Iso­cort, switching to Cor­tef or Hydro­cor­ti­sone should be con­si­de­red down the line. To find other pla­ces to order Iso­cort, just Goo­gle “Isocort”. 

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