Over the years, patients learned (or found out the hard way) that if they maintain taking certain supplements and certain medications up until doing saliva testing, they don’t get to see what they adrenals are doing “without influence”.

i.e. you only want to end up treating the natural state of your adrenal function, not the influenced state.

Below is a list of more common supplements or medications that can influence your adrenals.  Many patients state they stop taking as many of the over-the-counter supplements they can for up to two weeks before testing.

Some of the below are not easy to get off, or shouldn’t be stopped anyway!  For example, if depression would return by getting off 5-HTP, patients might nix getting off that. But most patients make the decision to get off as many as they can….or severely cut down.

A word of caution:  this page is for information only as to what can influence our adrenals.  Always work with your doctor with this information!


  1. Adrenal glandulars
  2. Adrenal Cortex (Isocort or other brands)
  3. Inositol
  4. Licorice Root
  5. 5-HTP
  6. Paba
  7. Progesterone via cream or gel
  8. Phosphatidyl serine (PS)
  9. Astragalus
  10. Ashwagandha
  11. Rhodiola
  12. Kava kava
  13. Holy Basil
  14. Siberian Ginseng (Eleuthero)
  15. Schizandra Berry
  16. Valerian
  17. Zinc
  18. Melatonin
  19. Cordyceps
  20. Theanine
  21. GABA
  22. Magnolia root extract
  23. Caffeine (from your coffee, tea or certain sodas, for example)
  24. Over-the-counter asthma supplements
  25. DHEA in higher amounts (it’s recommended to be off all DHEA for at least 72 hours)
  26. Flonase
  • HC (Hydrocortisone like Cortef and other brands)
  • Prednisone or Prednisolone
  • Medrol (aka Methylprednisone)
  • Florinef
  • Anti-depressants (whether Tricyclic or SSRI)
  • Anti-anxiety meds, aka Benzodiazepines or Benxo (Xanax is an example)
  • Blood Pressure medications
  • ADHD meds (Adderall for example)
  • Beta Blockers (Lopressor or Toprol XL, Atenolol or Tenormin, Labetalol like Normodyne and Trandate)
  • Asthma prescription meds or sprays
  • Sleeping Pills (such as Lunesta, Ambien)
  • Pain killers for arthritis
  • Pain killers for Migraines (aka Imitrex)  
  • Compounded Progesterone 

** Want to know more about adrenal issues? Click on the latter link.

** READ CHAPTER 6 in the revised STTM book for the best information anywhere on how to treat adrenals!

** Learn about the Seven Stages of Adrenal problems.

** Electrolytes and Minerals are important in all this.